Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoyl Chloride SCHEMBL8173965 | 0.84 | MEN1 (0.42) | ESR1ESR2HTTLMNAMAPT | |
| SCHEMBL9247156 | 0.84 | SRD5A2 (0.50) | MAPTHPGDSRD5A2CA1CA2 | |
| SCHEMBL9507319 | 0.84 | ALDH1A1 (0.52) | HTTLMNAMAPTPKMHPGD | |
| SCHEMBL9498504 | 0.82 | CES2 (0.45) | LMNAMAPTHPGDCA1CA2 | |
| SCHEMBL8167107 | 0.82 | CES2 (0.45) | HTTLMNAMAPTHPGDELANE | |
| SCHEMBL418096 | 0.82 | POLB (0.53) | MAPTHPGDELANEBLMCYP3A4 | |
| SCHEMBL7478788 | 0.79 | LOXL2 (0.49) | HPGDESRRGSMN1; SMN2 | |
| SCHEMBL8520681 | 0.79 | SMN1; SMN2 (0.58) | HTTLMNAMAPTHPGDCYP3A4 | |
| SCHEMBL9244501 | 0.78 | GSR (0.45) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8006902 | 0.78 | LOXL2 (0.47) | MAPTHPGDESRRGCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434079-B1 | N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives | ATOCHEM NORTH AMERICA (US) | 1995-09-20 | — | — | EP | disclosed |
| EP-0443540-A1 | Hindered phenolic N-(amido)-imides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1991-08-28 | — | — | EP | disclosed |
| EP-0434080-A1 | Derivatives of N-hals-substituted amic acid hydrazides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1991-06-26 | — | — | EP | disclosed |