Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 5/20 | 0.45 |
| ▸ | THRB | P10828 | 5/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.44 |
| ▸ | STS | P08842 | 4/20 | 0.43 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.41 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504731 | 0.85 | S1PR1 (0.47) | TNNC1SGPL1S1PR4S1PR1GPR183 | |
| SCHEMBL17301080 | 0.83 | THRA (0.50) | THRATHRBHSD17B3STS | |
| SCHEMBL15894876 | 0.79 | THRA (0.46) | THRATHRBHSD17B3STSS1PR1 | |
| SCHEMBL6527018 | 0.79 | RARB (0.41) | TNNC1SGPL1S1PR4S1PR1GPR183 | |
| SCHEMBL7622400 | 0.78 | THRA (0.46) | THRATHRBHSD17B3STSS1PR1 | |
| SCHEMBL7623199 | 0.78 | THRA (0.46) | THRATHRBHSD17B3STSS1PR1 | |
| SCHEMBL7622013 | 0.78 | THRA (0.46) | THRATHRBHSD17B3STSS1PR1 | |
| SCHEMBL7714029 | 0.77 | THRA (0.45) | THRATHRBHSD17B3STSS1PR1 | |
| SCHEMBL7613374 | 0.77 | THRA (0.45) | THRATHRBHSD17B3STSS1PR1 | |
| SCHEMBL4293988 | 0.77 | THRA (0.57) | THRATHRBHSD17B3STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11310556-A | — | — | None | — | — | JP | disclosed |