SCHEMBL8520979

SCHEMBL8520979

CCCCC(CC)C(O)C([C]=O)(CC)CC

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
CA2 P00918 7/20 0.33
MAPK1 P28482 1/20 0.33
CA1 P00915 4/20 0.32
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
FDPS P14324 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8521680 0.89 LMNA (0.34) LMNACA2MAPK1CA1ALDH1A1
SCHEMBL4889325 0.72 CA2 (0.36) LMNACA2MAPK1CA1ALDH1A1
SCHEMBL21536755 0.71 ALDH1A1 (0.37) LMNACA2MAPK1CA1ALDH1A1
SCHEMBL7128227 0.71 ALDH1A1 (0.37) LMNACA2MAPK1CA1ALDH1A1
SCHEMBL28377313 0.69 LMNA (0.39) LMNACA2MAPK1CA1ALDH1A1
SCHEMBL21291756 0.69 CA2 (0.38) LMNACA2MAPK1CA1ALDH1A1
Hydroxyl Radical SCHEMBL8682810 0.69 TSHR (0.39) LMNACA2MAPK1CA1ALDH1A1
SCHEMBL9959896 0.67 GPR84 (0.38) LMNACA2TSHR
SCHEMBL423728 0.67 ALDH1A1 (0.44) LMNACA2MAPK1CA1ALDH1A1
SCHEMBL12209116 0.67 ALDH1A1 (0.44) LMNACA2MAPK1CA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0761705-B1 Liquid one-component polyurethane storing lacquers DEGUSSA (DE) 1999-11-24 EP disclosed
EP-0761705-A1 Liquid one-component polyurethane storing lacquers HÜLS AKTIENGESELLSCHAFT (DE) 1997-03-12 EP disclosed
EP-0045997-B1 STOVING VARNISH HÜLS AKTIENGESELLSCHAFT (DE) 1985-10-16 EP disclosed
US-4355058-A STORAGE STABLE CURABLE EPOXY RESINS CHEMISCHE WERKE HUELS AKTIENGESELLSCHAFT (DE) 1982-10-19 US disclosed
EP-0001468-B1 POWDERED COATING PRODUCTS, PROCESS FOR THEIR PREPARATION AND THEIR USE CHEMISCHE WERKE HÜLS AG (DE) 1982-05-12 EP disclosed
EP-0045997-A1 Stoving varnish HÜLS AKTIENGESELLSCHAFT (DE) 1982-02-17 EP disclosed
EP-0001467-B1 STOVING LACQUERS HAVING AN EXTENDED POT LIFE ON THE BASIS OF POLYISOCYANATE MASKED WITH IMIDAZOLINES CHEMISCHE WERKE HÜLS AG (DE) 1981-10-21 EP disclosed
EP-0001148-B1 METHOD OF COATING GLASS SURFACES CHEMISCHE WERKE HÜLS AG (DE) 1981-09-30 EP disclosed
EP-0023023-A1 Pulverulent coating masses having an extended pot-life, and their preparation CHEMISCHE WERKE HÜLS AG (DE) 1981-01-28 EP disclosed
US-4246394-A PROMOTER FOR CROSSLINKING VEBA-CHEMIE AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
US-4242248-A WEATHER RESISTANT COIL COATING CHEMISCHE WERKE HULS AG (DE) 1980-12-30 US disclosed
US-4210687-A SHATTERPROOF COATING FOR BOTTLES CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DE) 1980-07-01 US disclosed
EP-0001467-A1 Stoving lacquers having an extended pot life on the basis of polyisocyanate masked with imidazolines CHEMISCHE WERKE HÜLS AG (DE) 1979-04-18 EP disclosed
EP-0001468-A1 Powdered coating products, process for their preparation and their use CHEMISCHE WERKE HÜLS AG (DE) 1979-04-18 EP disclosed