Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522094 | 1.00 | CYP2D6 (0.43) | CYP2D6CYP3A4ALDH1A1USP2MAPK1 | |
| SCHEMBL8522102 | 1.00 | CYP2D6 (0.43) | CYP2D6CYP3A4ALDH1A1USP2MAPK1 | |
| SCHEMBL8848434 | 0.79 | CHRNB2 (0.40) | CYP2D6ALDH1A1USP2CHRM2CHRM4 | |
| SCHEMBL8848447 | 0.79 | CHRNB2 (0.40) | CYP2D6ALDH1A1USP2CHRM2CHRM4 | |
| SCHEMBL8848438 | 0.79 | CHRNB2 (0.40) | CYP2D6ALDH1A1USP2CHRM2CHRM4 | |
| SCHEMBL8522579 | 0.78 | CHRNB2 (0.42) | ALDH1A1USP2TSHRHTTCHRNB2 | |
| SCHEMBL7241335 | 0.77 | SIGMAR1 (0.55) | CYP2D6CYP3A4ALDH1A1USP2MAPK1 | |
| SCHEMBL8309536 | 0.73 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL8308796 | 0.73 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL8308800 | 0.73 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607374-B1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | PO HANG IRON & STEEL (KR) | 1999-04-07 | — | — | EP | disclosed |
| US-5610310-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD (KR) | 1997-03-11 | — | — | US | disclosed |
| EP-0607374-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994000447-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-01-06 | — | — | WO | disclosed |