Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848447 | 0.84 | CHRNB2 (0.40) | CHRNB2CHRNA7CHRNA4CHRNA5ELANE | |
| SCHEMBL8848438 | 0.84 | CHRNB2 (0.40) | CHRNB2CHRNA7CHRNA4CHRNA5ELANE | |
| SCHEMBL8848434 | 0.84 | CHRNB2 (0.40) | CHRNB2CHRNA7CHRNA4CHRNA5ELANE | |
| SCHEMBL8522102 | 0.78 | CYP2D6 (0.43) | CHRNB2CHRNA7CHRNA4CHRNA5ALDH1A1 | |
| SCHEMBL8522094 | 0.78 | CYP2D6 (0.43) | CHRNB2CHRNA7CHRNA4CHRNA5ALDH1A1 | |
| SCHEMBL8522099 | 0.78 | CYP2D6 (0.43) | CHRNB2CHRNA7CHRNA4CHRNA5ALDH1A1 | |
| SCHEMBL8308864 | 0.74 | SIGMAR1 (0.44) | CHRNB2CHRNA7CHRNA4KDM4EALDH1A1 | |
| SCHEMBL8308862 | 0.74 | SIGMAR1 (0.44) | CHRNB2CHRNA7CHRNA4KDM4EALDH1A1 | |
| SCHEMBL8308867 | 0.74 | SIGMAR1 (0.44) | CHRNB2CHRNA7CHRNA4KDM4EALDH1A1 | |
| SCHEMBL8308796 | 0.73 | SMN1; SMN2 (0.38) | KDM4EALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607374-B1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | PO HANG IRON & STEEL (KR) | 1999-04-07 | — | — | EP | disclosed |
| EP-0607374-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994000447-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-01-06 | — | — | WO | disclosed |