Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521495 | 0.85 | PLA2G2A (0.51) | ALDH1A1KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL8446764 | 0.80 | CNR1 (0.58) | KMT2AMAPT | |
| SCHEMBL6973555 | 0.78 | ACHE (0.48) | LMNAALDH1A1KMT2AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL8628457 | 0.78 | HRH1 (0.52) | GAAALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL8624583 | 0.77 | HRH1 (0.46) | TP53ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL8450448 | 0.76 | AKR1C3 (0.51) | KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL8625863 | 0.76 | PLA2G2A (0.53) | GAAALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL8522103 | 0.75 | GAA (0.49) | LMNAGAATP53ALDH1A1KMT2A | |
| SCHEMBL8522105 | 0.75 | GAA (0.49) | LMNAGAATP53ALDH1A1KMT2A | |
| SCHEMBL8627812 | 0.75 | GABRA1 (0.48) | KMT2AMEN1HRH3POLBGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776932-A | ANTIALLERGENS, ANTIASTHMATICS, ANTIINFLAMMATORY AGENTS AND MODULATORS | ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) | 1998-07-07 | — | — | US | claimed |
| EP-0888307-A1 | 1,3,5-TRISUBSTITUTED INDAZOLE DERIVATIVES WITH AN ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING ACTION | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1999-01-07 | — | — | EP | disclosed |
| US-5776932-A | ANTIALLERGENS, ANTIASTHMATICS, ANTIINFLAMMATORY AGENTS AND MODULATORS | ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) | 1998-07-07 | — | — | US | disclosed |
| WO-1997034874-A1 | 1,3,5-TRISUBSTITUTED INDAZOLE DERIVATIVES WITH AN ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING ACTION | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1997-09-25 | — | — | WO | disclosed |