Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521495 | 0.89 | PLA2G2A (0.51) | HRH1HTR6PLA2G2AMTNR1AMTNR1B | |
| SCHEMBL8627206 | 0.85 | BUB1 (0.44) | HRH1HTR6MAOAMAOBNAMPT | |
| SCHEMBL8522112 | 0.77 | LMNA (0.43) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8627812 | 0.76 | GABRA1 (0.48) | PLA2G2ASIGMAR1POLBMEN1KMT2A | |
| SCHEMBL8448659 | 0.76 | CNR1 (0.52) | HTR6ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8444741 | 0.75 | KCNJ1 (0.53) | ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8628457 | 0.74 | HRH1 (0.52) | HRH1HTR6PLA2G2AACP1KDM4E | |
| SCHEMBL8625692 | 0.74 | GABRA1 (0.49) | MAOAMAOBKDM4EALDH1A1MEN1 | |
| SCHEMBL8448874 | 0.73 | MAPT (0.49) | PLA2G2AALDH1A1ADRB2MEN1KMT2A | |
| SCHEMBL8522034 | 0.72 | CNR2 (0.50) | HTR6KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776932-A | ANTIALLERGENS, ANTIASTHMATICS, ANTIINFLAMMATORY AGENTS AND MODULATORS | ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) | 1998-07-07 | — | — | US | claimed |
| US-5776932-A | ANTIALLERGENS, ANTIASTHMATICS, ANTIINFLAMMATORY AGENTS AND MODULATORS | ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) | 1998-07-07 | — | — | US | disclosed |