Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.36 |
| ▸ | MIF | P14174 | 10/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ITGAM | P11215 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508461 | 0.83 | MIF (0.38) | NPC1RAB9AMIFHDAC6 | |
| SCHEMBL7502963 | 0.74 | MIF (0.40) | MIF | |
| SCHEMBL7502407 | 0.73 | MIF (0.35) | RAB9AMIF | |
| SCHEMBL7505315 | 0.67 | MIF (0.38) | NPC1RAB9AMIFHDAC6 | |
| SCHEMBL7505771 | 0.63 | MIF (0.38) | NPC1RAB9AMIFHDAC6 | |
| SCHEMBL14350426 | 0.62 | QDPR (0.49) | MIFHDAC6 | |
| SCHEMBL7507435 | 0.62 | MIF (0.42) | RAB9AMIF | |
| SCHEMBL7504359 | 0.61 | QDPR (0.46) | NPC1RAB9AMIFHDAC6 | |
| SCHEMBL7505583 | 0.61 | RAB9A (0.45) | NPC1RAB9AMIFHDAC6 | |
| SCHEMBL12556312 | 0.60 | MIF (0.74) | NPC1RAB9AITGB3ITGA2BMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920421-A1 | ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1999-06-09 | — | — | EP | claimed |
| WO-1998007708-A1 | ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1998-02-26 | — | — | WO | claimed |