Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049057 | 0.83 | GRIK1 (0.55) | KMT2AMTNR1AMTNR1BPDE5AGRIK1 | |
| SCHEMBL28979220 | 0.82 | PDE5A (0.62) | KMT2APDE5AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2797929 | 0.79 | KMT2A (0.48) | KMT2AMTNR1AMTNR1BPDE5AGRM2 | |
| SCHEMBL8368861 | 0.78 | PTGS1 (0.50) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6074279 | 0.78 | BRPF1 (0.59) | KMT2AMTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL8366395 | 0.77 | MAPT (0.52) | KMT2AMTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL4055635 | 0.77 | GRIK1 (0.46) | MTNR1AMTNR1BGRIK1GRIK2KDM4E | |
| SCHEMBL4056506 | 0.75 | ALDH1A1 (0.45) | MTNR1AMTNR1BGRIK1GRIK2KDM4E | |
| SCHEMBL3817124 | 0.75 | HTR2C (0.59) | KMT2AMTNR1AMTNR1BKDM4EL3MBTL1 | |
| SCHEMBL2799788 | 0.75 | KMT2A (0.44) | KMT2AMTNR1AMTNR1BPDE5AGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850235-B1 | QUINOLEIN-2(1H)-ONE DERIVATIVES AS SEROTONIN ANTAGONISTS | SANOFI SYNTHELABO (FR) | 1999-12-01 | — | — | EP | disclosed |