SCHEMBL852265

SCHEMBL852265

COc1cc(C(C)(C)C)cc(C(C)(C)C)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.53
CA1 P00915 3/20 0.53
CYP3A4 P08684 2/20 0.50
ALOX15 P16050 2/20 0.50
LMNA P02545 2/20 0.50
TP53 P04637 1/20 0.50
HPGD P15428 1/20 0.50
HSP90AA1 P07900 1/20 0.44
ALDH1A1 P00352 2/20 0.43
POLB P06746 1/20 0.43
TYR P14679 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CYP1A2 P05177 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
TSHR P16473 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
PTGS2 P35354 2/20 0.40
PTGS1 P23219 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10028316 0.87 LMNA (0.48) CA2CA1CYP3A4ALOX15LMNA
Methane SCHEMBL20485779 0.85 LMNA (0.47) CA2CA1CYP3A4ALOX15LMNA
SCHEMBL8739936 0.83 EGFR (0.49) CA2CA1CYP3A4ALOX15LMNA
SCHEMBL20312930 0.82 ERBB2 (0.47) CA2CA1CYP3A4ALOX15LMNA
SCHEMBL19351183 0.82 TNKS2 (0.46) CA2CA1CYP3A4ALOX15LMNA
SCHEMBL10015238 0.82 EGFR (0.45) CA2CA1CYP3A4ALOX15LMNA
SCHEMBL35141 0.80 CA2 (0.67) CA2CA1CYP3A4ALOX15LMNA
SCHEMBL16014947 0.80 CA2 (0.46) CA2CA1CYP3A4ALOX15LMNA
SCHEMBL679047 0.80 CA2 (0.65) CA2CA1CYP3A4ALOX15LMNA
SCHEMBL852671 0.80 CA2 (0.77) CA2CA1CYP3A4ALOX15LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3943239-A PYRETHROID SUMITOMO CHEMICAL CO., LTD. (JA) 1976-03-09 US claimed
US-9882137-B2 Organic semiconductor composition, organic thin film transistor, electronic paper, and display device FUJIFILM CORPORATION (JP) 2018-01-30 US disclosed
US-9882137-B2 Organic semiconductor composition, organic thin film transistor, electronic paper, and display device FUJIFILM CORPORATION (JP) 2018-01-30 US disclosed
US-9795549-B2 1,2-alkane polyol-containing composition OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2017-10-24 US disclosed
US-20170179387-A1 ORGANIC SEMICONDUCTOR COMPOSITION, ORGANIC THIN FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-06-22 US disclosed
US-20170179387-A1 ORGANIC SEMICONDUCTOR COMPOSITION, ORGANIC THIN FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-06-22 US disclosed
WO-2017015765-A1 MAGNETICALLY BISTABLE COMPLEXES AND DEVICES AND METHODS OF MAKING AND USING THE SAME UVIC INDUSTRY PARTNERSHIPS INC. (CA) 2017-02-02 WO disclosed
US-9273238-B2 Process for fungal modification of lignin and preparing wood adhesives with the modified lignin and wood composites made from such adhesives FPINNOVATIONS (CA) 2016-03-01 US disclosed
US-9273238-B2 Process for fungal modification of lignin and preparing wood adhesives with the modified lignin and wood composites made from such adhesives FPINNOVATIONS (CA) 2016-03-01 US disclosed
US-20160045414-A1 1,2-ALKANE POLYOL-CONTAINING COMPOSITION OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2016-02-18 US disclosed
EP-1655343-A1 CROSSLINKABLE RESIN COMPOSITION AND RESIN FORMED BODY PRODUCED THEREFROM Zeon Corporation (JP) 2006-05-10 EP disclosed
EP-1655319-A1 POLYMERIZABLE COMPOSITION AND FORMED BODY THEREOF Zeon Corporation (JP) 2006-05-10 EP disclosed
EP-1655321-A1 POLYMERIZABLE COMPOSITIONS AND MOLDED ARTICLES PRODUCED BY USING THE SAME Zeon Corporation (JP) 2006-05-10 EP disclosed
CN-1735631-A Grafting of nitroxyl terminated oligomers or polymers onto thermoplastic polymers CIBA SC HOLDING AG (CH) 2006-02-15 CN disclosed
CN-1675278-A Thermoplastic resin, crosslinked resin, and method for producing crosslinked resin composite material ZEON CORP (JP) 2005-09-28 CN disclosed
EP-1535941-A1 PROCESSES FOR PRODUCING THERMOPLASTIC RESINS, CROSSLINKED RESINS AND CROSSLINKED RESIN COMPOSITE MATERIALS ZEON CORPORATION (JP) 2005-06-01 EP disclosed
US-20040204521-A1 Additive functionalized organophilic nano-scaled fillers CIBA SPECIALTY CHEMICALS CORP. 2004-10-14 US disclosed
US-6365651-B1 Synergistic stabilizer mixture CIBA SPECIALTY CHEMICALS CORPORATION 2002-04-02 US disclosed
US-6359148-B1 FOR POLYMER, LUBRICANTS; HEAT, OXIDATION RESISTANCE, PHOTOSTABILITY NESVADBA PETER (CH) 2002-03-19 US disclosed
EP-0210907-A1 Process for the preparation of methacrylic esters by transesterification SOCIETE FRANCAISE D'ORGANO-SYNTHESE (FR) 1987-02-04 EP disclosed