Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10028316 | 0.91 | LMNA (0.48) | EGFRHPGDALOX15LMNACYP3A4 | |
| Methane SCHEMBL20485779 | 0.89 | LMNA (0.47) | EGFRHPGDALOX15LMNACYP3A4 | |
| SCHEMBL10015238 | 0.85 | EGFR (0.45) | EGFRHPGDALOX15LMNACYP3A4 | |
| SCHEMBL19351183 | 0.85 | TNKS2 (0.46) | EGFRHPGDALOX15LMNACYP3A4 | |
| SCHEMBL7843399 | 0.83 | TPMT (0.50) | HPGDALOX15LMNACYP3A4TP53 | |
| SCHEMBL1425172 | 0.83 | HPGD (0.46) | EGFRHPGDALOX15LMNACYP3A4 | |
| SCHEMBL30455185 | 0.83 | HPGD (0.46) | EGFRHPGDALOX15LMNACYP3A4 | |
| SCHEMBL852265 | 0.83 | CA2 (0.53) | EGFRHPGDALOX15LMNACYP3A4 | |
| SCHEMBL11790827 | 0.82 | ALOX5 (0.60) | EGFRHPGDALOX15LMNACYP3A4 | |
| SCHEMBL3872595 | 0.81 | GABRA1 (0.57) | EGFRHPGDALOX15LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11040987-B2 | Penam derivatives for treating bacterial infections | TENNOR THERAPEUTICS LIMITED (CN) | 2021-06-22 | — | — | US | disclosed |
| US-20200237708-A1 | 9,10-Alpha,Alpha-OH-Taxane Analogs and Methods for Production Thereof | TAPESTRY PHARMACEUTICALS, INC. | 2020-07-30 | — | — | US | disclosed |
| US-10238621-B2 | 9,10-α,α-OH-taxane analogs and methods for production thereof | TAPESTRY PHARMACEUTICALS, INC. (US) | 2019-03-26 | — | — | US | disclosed |
| US-9820962-B2 | 9, 10-α, α-oh-taxane analogs and methods for production thereof | TAPESTRY PHARMACEUTICALS, INC. (US) | 2017-11-21 | — | — | US | disclosed |
| US-20150073045-A1 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO | CORNELL UNIVERSITY (US) | 2015-03-12 | — | — | US | disclosed |
| US-8563603-B2 | Polycyclic compounds and methods related thereto | CORNELL UNIVERSITY (US) | 2013-10-22 | — | — | US | disclosed |
| US-20120130147-A1 | METHODS FOR THE TREATMENT OF TUMORS WITH INDANE COMPOUNDS | FINSINGER DIRK (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120077871-A1 | 9, 10-Alpha, Alpha-OH-Taxane Analogs and Methods for Production Thereof | TAPESTRY PHARMACEUTICALS, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| US-20110275708-A1 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO | CORNELL UNIVERSITY (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110275708-A1 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO | CORNELL UNIVERSITY (US) | 2011-11-10 | — | — | US | disclosed |
| WO-2010048452-A2 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO | CHAVEZ KATHRYN JILL (US) | 2010-04-29 | — | — | WO | disclosed |
| US-20090118267-A1 | INDANES | MERCK PATENT GMBH (DE) | 2009-05-07 | — | — | US | disclosed |
| US-7455948-B2 | Photosensitive resin composition | TORAY INDUSTRIES, INC. (JP) | 2008-11-25 | — | — | US | disclosed |
| US-20070219246-A1 | Dihydrobenzothiophenes | MERCK PATENT GMBH (DE) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130147-A1 | METHODS FOR THE TREATMENT OF TUMORS WITH INDANE COMPOUNDS | TP53, IDH3A, IDH2 | EGFR 267/4885HPGD 727/4885ALOX15 2195/4885 |
| US-20090118267-A1 | INDANES | IDH3A, CYP1A1, CCNT1 | EGFR 1899/4885HPGD 735/4885ALOX15 1498/4885 |
| US-20150073045-A1 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO | PKD1, THPO, CCNO | EGFR 413/4885HPGD 374/4885ALOX15 24/4885 |
| US-20120077871-A1 | 9, 10-Alpha, Alpha-OH-Taxane Analogs and Methods for Production Thereof | TECR, ADCY9, AKR1C3 | EGFR 1605/4885HPGD 1020/4885ALOX15 1393/4885 |
| US-11040987-B2 | Penam derivatives for treating bacterial infections | BPGM, BLVRB, PREP | EGFR 3267/4885HPGD 916/4885ALOX15 1635/4885 |
| US-20110275708-A1 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO | PKD1, THPO, CCNO | EGFR 380/4885HPGD 338/4885ALOX15 23/4885 |
| US-20200237708-A1 | 9,10-Alpha,Alpha-OH-Taxane Analogs and Methods for Production Thereof | ADCY9, TECR, AKR1C3 | EGFR 1545/4885HPGD 1222/4885ALOX15 902/4885 |
| US-10238621-B2 | 9,10-α,α-OH-taxane analogs and methods for production thereof | TECR, AKR1C3, ADCY9 | EGFR 1217/4885HPGD 928/4885ALOX15 1350/4885 |
| US-20070219246-A1 | Dihydrobenzothiophenes | CCNT1, CCNT2, TPT1 | EGFR 1164/4885HPGD 1621/4885ALOX15 2852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.