Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | TYR | P14679 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16024770 | 0.89 | CA2 (0.57) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL30898481 | 0.86 | SMN1; SMN2 (0.68) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL6244864 | 0.86 | SMN1; SMN2 (0.68) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL453824 | 0.80 | SMN1; SMN2 (1.00) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL3950 | 0.80 | SMN1; SMN2 (1.00) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL562147 | 0.80 | ERN1 (0.63) | CA2SMN1; SMN2ALDH1A1POLBCA1 | |
| SCHEMBL16014947 | 0.80 | CA2 (0.46) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL852265 | 0.80 | CA2 (0.53) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL852671 | 0.80 | CA2 (0.77) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL11857289 | 0.78 | SMN1; SMN2 (0.95) | CA2SMN1; SMN2ALDH1A1POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284638-A1 | ALPHAvBETA1 INTEGRIN ANTAGONISTS | SAINT LOUIS UNIVERSITY (US) | 2021-09-16 | — | — | US | disclosed |
| US-20210284638-A1 | ALPHAvBETA1 INTEGRIN ANTAGONISTS | SAINT LOUIS UNIVERSITY (US) | 2021-09-16 | — | — | US | disclosed |
| US-9795549-B2 | 1,2-alkane polyol-containing composition | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2017-10-24 | — | — | US | disclosed |
| US-20160045414-A1 | 1,2-ALKANE POLYOL-CONTAINING COMPOSITION | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2016-02-18 | — | — | US | disclosed |
| EP-2985017-A1 | 1,2-ALKANE POLYOL-CONTAINING COMPOSITION | Osaka Organic Chemical Ind., Ltd. (JP) | 2016-02-17 | — | — | EP | disclosed |
| US-8067464-B2 | Compositions and methods using apocynin compounds and nitric oxide donors | NITROMED, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-20090203653-A1 | Compositions and Methods Using Apocynin Compounds and Nitric Oxide Donors | NITROMED, INC. (US) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284638-A1 | ALPHAvBETA1 INTEGRIN ANTAGONISTS | ITGB1, ITGAV, ITGA1 | CA2 1928/4885SMN1; SMN2 2205/4885ALDH1A1 441/4885 |
| US-20090203653-A1 | Compositions and Methods Using Apocynin Compounds and Nitric Oxide Donors | NOX4, NOS2, REN | CA2 940/4885SMN1; SMN2 3735/4885ALDH1A1 574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.