Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8182722 | 0.82 | KDR (0.43) | KDRMEN1KMT2AKLKB1PTGES | |
| SCHEMBL8184224 | 0.79 | MEN1 (0.44) | KDRMEN1KMT2AKLKB1RXFP1 | |
| SCHEMBL8068248 | 0.78 | MEN1 (0.43) | KDRMEN1KMT2AKLKB1RXFP1 | |
| SCHEMBL7792082 | 0.77 | MEN1 (0.42) | KDRMEN1KMT2ARXFP1PTGES | |
| SCHEMBL7799989 | 0.77 | ALDH1A1 (0.44) | KDRMEN1KMT2A | |
| SCHEMBL8184203 | 0.77 | KMT2A (0.42) | MEN1KMT2ARXFP1 | |
| SCHEMBL8184226 | 0.77 | KMT2A (0.46) | KDRMEN1KMT2APPARGPPARD | |
| SCHEMBL8174302 | 0.77 | KMT2A (0.46) | MEN1KMT2A | |
| SCHEMBL8176105 | 0.76 | MEN1 (0.44) | KDRMEN1KMT2ANPY5RKLKB1 | |
| SCHEMBL8604955 | 0.76 | HTR1F (0.46) | MEN1KMT2AHTR1FCARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906283-A1 | SUBSTITUTED BENZAMIDE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997048683-A1 | SUBSTITUTED BENZAMIDE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 1997-12-24 | — | — | WO | disclosed |