Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 2/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | CPA3 | P15088 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22242591 | 0.77 | FOLH1 (0.46) | FOLH1TDP1SMN1; SMN2CPA1CPB1 | |
| SCHEMBL30018930 | 0.75 | FOLH1 (0.65) | FOLH1TDP1SMN1; SMN2CPA1CPB1 | |
| SCHEMBL1052505 | 0.74 | TDP1 (0.48) | FOLH1TDP1SMN1; SMN2CPA1CPB1 | |
| SCHEMBL4321051 | 0.74 | TDP1 (0.48) | FOLH1TDP1SMN1; SMN2CPA1CPB1 | |
| SCHEMBL164322 | 0.71 | FOLH1 (0.75) | FOLH1TDP1SMN1; SMN2CPA1CPB1 | |
| SCHEMBL21802279 | 0.71 | FOLH1 (0.75) | FOLH1TDP1SMN1; SMN2CPA1CPB1 | |
| SCHEMBL2177182 | 0.70 | FOLH1 (0.41) | FOLH1TDP1SMN1; SMN2CPA1CPB1 | |
| SCHEMBL742785 | 0.70 | FOLH1 (0.54) | FOLH1 | |
| SCHEMBL9668057 | 0.69 | MMP2 (0.40) | FOLH1TDP1SMN1; SMN2SLC22A6 | |
| SCHEMBL31040679 | 0.68 | GPR84 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910362-A4 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 1999-12-22 | — | — | EP | disclosed |
| EP-0910362-A1 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PRODUCTS, INC. (US) | 1999-04-28 | — | — | EP | disclosed |