Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523298 | 0.83 | DGAT1 (0.33) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL18801577 | 0.82 | ALDH1A1 (0.31) | ALDH1A1LMNA | |
| SCHEMBL8462922 | 0.80 | TSHR (0.32) | ALDH1A1THRBTSHRTDP1 | |
| SCHEMBL16205893 | 0.80 | ALDH1A1 (0.31) | SMN1; SMN2ALDH1A1HIF1A | |
| SCHEMBL17460816 | 0.80 | HDAC3 (0.34) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL28514999 | 0.78 | HDAC3 (0.33) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8868668 | 0.78 | HDAC6 (0.37) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL27403835 | 0.78 | HDAC6 (0.37) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL27945867 | 0.78 | HTT (0.32) | HTT | |
| SCHEMBL2740502 | 0.78 | HDAC6 (0.37) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088786-A | Eptification intermediate and preparation method thereof | 上海医药工业研究院有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-111019225-B | Anti-static anti-fouling plastic film for packaging | 浙江保禄包装科技股份有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-109415513-B | Silicon-rich silsesquioxane resins | 美国陶氏有机硅公司 | 2022-02-25 | — | — | CN | claimed |
| CN-113152086-A | Antibacterial moisture-absorption breathable fabric | 刘利红 | 2021-07-23 | — | — | CN | claimed |
| CN-112981956-A | Moisture-absorbing breathable jean fabric | 张霞 | 2021-06-18 | — | — | CN | claimed |
| CN-111019225-A | Anti-static anti-fouling plastic film for packaging | 田朝义 | 2020-04-17 | — | — | CN | claimed |
| CN-110515271-A | A kind of photosensitive polymer combination and its application | HANGZHOU FIRST APPLIED MAT CO LTD | 2019-11-29 | — | — | CN | claimed |
| US-20190211155-A1 | SILICON-RICH SILSESQUIOXANE RESINS | DOW SILICONES CORPORATION | 2019-07-11 | — | — | US | claimed |
| CN-109913195-A | A kind of package acid improving acid fracturing EFFECTIVE RANGE | 西南石油大学 | 2019-06-21 | — | — | CN | claimed |
| CN-109415513-A | Silsesquioxane resins rich in silicon | 美国陶氏有机硅公司 | 2019-03-01 | — | — | CN | claimed |
| CN-100427518-C | Flame-proof acrylic resin for reflecting cloth | NANJING YESHILI FINE CHEMICAL (CN) | 2008-10-22 | — | — | CN | claimed |
| EP-4029868-B1 | MCL-1 INHIBITORS | GILEAD SCIENCES INC (US) | 2026-05-20 | — | — | EP | disclosed |
| US-20260116891-A1 | Oxazepin Derivative | TEIJIN PHARMA LTD (JP) | 2026-04-30 | — | — | US | disclosed |
| US-20260115296-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES | UNIV YALE (US) | 2026-04-30 | — | — | US | disclosed |
| EP-3886904-B1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-04-22 | — | — | EP | disclosed |
| CN-88100500-A | NOVEL POLYAMINE DERIVATIVES | — | 1988-09-07 | — | — | CN | disclosed |
| EP-0169176-A1 | Tert-butyl gamma dimethylamino beta-hydroxy butyrate and process for its preparation | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1986-01-22 | — | — | EP | disclosed |
| US-4414153-A | 1,3-Dithietane-2-carboxylic acid penicillin and cephalosporin derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1983-11-08 | — | — | US | disclosed |
| US-4198339-A | INTERMEDIATES FOR PENICILLINS AND CEPHALOSPORINS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1980-04-15 | — | — | US | disclosed |
| US-3946054-A | PERFUMES, TOBACCO, FOOD FLAVORS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260115296-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES | CRBN, VHL, ADRM1 | HDAC3 3022/4885HDAC1 2489/4885HDAC2 3533/4885 |
| US-20260116891-A1 | Oxazepin Derivative | HCRTR2, HCRTR1, OXTR | HDAC3 326/4885HDAC1 574/4885HDAC2 529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.