Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | MTTP | P55157 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483448 | 0.90 | POLB (0.33) | SLC6A2SLC6A3POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8479995 | 0.89 | MEN1 (0.36) | ALDH1A1KMT2AMEN1MTTPMAPT | |
| SCHEMBL8653095 | 0.88 | PRMT5 (0.33) | POLBMTTP | |
| SCHEMBL8480386 | 0.87 | POLB (0.33) | POLBALDH1A1LMNAGAA | |
| SCHEMBL8479937 | 0.85 | MEN1 (0.35) | ALDH1A1KMT2AMEN1MTTPMAPT | |
| SCHEMBL8667993 | 0.84 | ACKR3 (0.37) | SLC6A2SLC6A3POLBCYP2C9ALDH1A1 | |
| SCHEMBL8503674 | 0.79 | CCR2 (0.36) | SLC6A2SLC6A3POLBACKR3MTTP | |
| SCHEMBL8662744 | 0.78 | ACKR3 (0.36) | SLC6A2SLC6A3CYP2C9ALDH1A1SLC6A4 | |
| SCHEMBL8523535 | 0.77 | KMT2A (0.40) | POLBCYP2C9ALDH1A1KMT2AMEN1 | |
| SCHEMBL8668004 | 0.75 | POLB (0.37) | POLBCYP2C9ALDH1A1ACKR3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883099-A | TREATMENT OF ATHERSCLEROSIS, PANCREATITIS OBESITY OR HYPERGLYCEMIA | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-16 | — | — | US | disclosed |