Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667993 | 0.87 | ACKR3 (0.37) | ACKR3CYP1A2TRPA1SLC6A2SLC6A3 | |
| SCHEMBL8662754 | 0.78 | ALDH1A1 (0.34) | ACKR3CYP1A2HTTMAPTALDH1A1 | |
| SCHEMBL8523531 | 0.78 | SLC6A2 (0.34) | ACKR3CYP1A2SLC6A2SLC6A3LMNA | |
| SCHEMBL8667920 | 0.77 | UBE2M (0.36) | ACKR3KDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL8503674 | 0.76 | CCR2 (0.36) | ACKR3SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL8663911 | 0.76 | UBE2M (0.36) | ACKR3KDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL8501140 | 0.76 | POLB (0.35) | CYP1A2GAAHTTMAPTALDH1A1 | |
| SCHEMBL8504387 | 0.75 | UBE2M (0.36) | ACKR3ALDH1A1KDM4EMEN1MAPK1 | |
| SCHEMBL8662751 | 0.75 | KMT2A (0.35) | ACKR3CYP1A2GAAMAPTTP53 | |
| SCHEMBL8483448 | 0.70 | POLB (0.33) | SLC6A2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |