Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 10/20 | 0.51 |
| ▸ | EDNRB | P24530 | 9/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479988 | 0.86 | EDNRA (0.55) | EDNRAEDNRBTSHRMAPK1 | |
| SCHEMBL8473239 | 0.84 | EDNRA (0.52) | EDNRAEDNRBTSHRMAPK1 | |
| SCHEMBL8477061 | 0.82 | EDNRA (0.50) | EDNRAEDNRBTSHRMAPK1 | |
| SCHEMBL8473816 | 0.81 | NMT1 (0.43) | EDNRAEDNRBKDM4ETSHRMAPK1 | |
| SCHEMBL8525137 | 0.81 | EDNRA (0.55) | EDNRAEDNRBTSHRMAPK1 | |
| SCHEMBL8476607 | 0.79 | EDNRA (0.53) | EDNRAEDNRBTSHRMAPK1 | |
| SCHEMBL7221292 | 0.79 | EDNRA (0.71) | EDNRAEDNRBTSHR | |
| SCHEMBL8481520 | 0.78 | EDNRA (0.50) | EDNRAEDNRBTSHRMAPK1 | |
| SCHEMBL8478164 | 0.75 | HSD11B1 (0.49) | EDNRAEDNRB | |
| SCHEMBL8479939 | 0.73 | ALDH1A1 (0.49) | EDNRAEDNRBKDM4ETSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859257-A | ANTIINFLAMMATORY, ANTIARTHRITIC AGENTS | G. D. SEARLE & CO. (US) | 1999-01-12 | — | — | US | disclosed |