Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576596 | 0.78 | CACNA1G (0.39) | ALDH1A1POLBMAPTGAACHRM1 | |
| SCHEMBL8573201 | 0.77 | POLB (0.37) | ALDH1A1POLBMAPTGAACHRM1 | |
| SCHEMBL8572927 | 0.75 | POLB (0.39) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL8575184 | 0.74 | POLB (0.38) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL3774754 | 0.73 | MAPT (0.50) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8577715 | 0.73 | POLB (0.35) | ALDH1A1CDK4POLBMAPTL3MBTL1 | |
| SCHEMBL6032173 | 0.72 | MAPT (0.54) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL8523852 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL8576765 | 0.72 | POLB (0.36) | ALDH1A1POLBMAPTL3MBTL1GAA | |
| SCHEMBL8573028 | 0.72 | POLB (0.36) | ALDH1A1POLBMAPTL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834501-A | TREATING DIABETES OR HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 1998-11-10 | — | — | US | claimed |
| US-5962470-A | Heterocyclic compounds having anti-diabetic activity and their use | SANKYO COMPANY, LIMITED (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5739345-A | HYPOGLYCEMIC AND ANTIDIABETIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |