Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 2/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996718 | 1.00 | SLC6A2 (0.34) | SLC6A2SLC6A3SLC6A4MBOAT4HRH1 | |
| SCHEMBL8523925 | 0.91 | TRPC6 (0.35) | MBOAT4HRH1 | |
| SCHEMBL8996728 | 0.91 | TRPC6 (0.35) | MBOAT4HRH1 | |
| SCHEMBL8524427 | 0.87 | SRD5A1 (0.33) | SLC6A2SLC6A3SLC6A4SRD5A1SRD5A2 | |
| SCHEMBL8524175 | 0.87 | SRD5A1 (0.36) | SRD5A1SRD5A2 | |
| SCHEMBL8996733 | 0.83 | STS (0.30) | SRD5A1SRD5A2 | |
| SCHEMBL8523662 | 0.83 | STS (0.30) | SRD5A1SRD5A2 | |
| SCHEMBL8523102 | 0.82 | KDM4E (0.34) | SRD5A1SRD5A2 | |
| SCHEMBL8522770 | 0.82 | PLA2G7 (0.33) | SRD5A1 | |
| SCHEMBL8523449 | 0.82 | SRD5A1 (0.33) | SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786999-A4 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO INC (US) | 1999-01-20 | — | — | EP | claimed |
| EP-0792371-A4 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO INC (US) | 1998-12-30 | — | — | EP | claimed |
| EP-0792371-A1 | COMBINATION METHOD FOR ACNE TREATMENT | Merck & Co., Inc. (US) | 1997-09-03 | — | — | EP | claimed |
| EP-0786999-A1 | COMBINATION METHOD FOR ACNE TREATMENT | Merck & Co., Inc. (US) | 1997-08-06 | — | — | EP | claimed |
| EP-0724592-A1 | 16-SUBSTITUTED-4-AZA-ANDROSTANE 5-ALPHA-REDUCTASE ISOZYME 1 INHIBITORS | MERCK & CO. INC. (US) | 1996-08-07 | — | — | EP | claimed |
| WO-1996012487-A1 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO., INC. (US) | 1996-05-02 | — | — | WO | claimed |
| WO-1996012817-A1 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO., INC. (US) | 1996-05-02 | — | — | WO | claimed |
| WO-1995011254-A1 | 16-SUBSTITUTED-4-AZA-ANDROSTANE 5-ALPHA-REDUCTASE ISOZYME 1 INHIBITORS | MERCK & CO., INC. (US) | 1995-04-27 | — | — | WO | claimed |
| EP-0724592-A1 | 16-SUBSTITUTED-4-AZA-ANDROSTANE 5-ALPHA-REDUCTASE ISOZYME 1 INHIBITORS | MERCK & CO. INC. (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011254-A1 | 16-SUBSTITUTED-4-AZA-ANDROSTANE 5-ALPHA-REDUCTASE ISOZYME 1 INHIBITORS | MERCK & CO., INC. (US) | 1995-04-27 | — | — | WO | disclosed |