Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081352 | 0.86 | TDP1 (0.31) | TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6969765 | 0.85 | SMN1; SMN2 (0.31) | TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6965901 | 0.85 | RAB9A (0.35) | TDP1NPC1RAB9ASMN1; SMN2PTGDR2 | |
| SCHEMBL6966452 | 0.77 | HRH1 (0.32) | — | |
| SCHEMBL6968851 | 0.77 | NPC1 (0.31) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6972231 | 0.76 | NPC1 (0.30) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6970972 | 0.76 | HRH1 (0.31) | — | |
| SCHEMBL6968520 | 0.75 | RAB9A (0.35) | TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7081079 | 0.74 | HSP90B1 (0.33) | SMN1; SMN2 | |
| SCHEMBL6964951 | 0.74 | ALDH1A1 (0.32) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |