Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL5813768 | 0.91 | CTNNB1 (0.38) | PARP1NOTUMTRPM8TSHRCYP2C19 | |
| SCHEMBL29788643 | 0.88 | MAOA (0.41) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL895328 | 0.88 | MAOA (0.41) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL107468 | 0.88 | MAOA (0.41) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL29788642 | 0.88 | MAOA (0.41) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL8517 | 0.88 | MAOA (0.41) | TSHRCA12CA1CA2CA9 | |
| Formaldehyde SCHEMBL28062094 | 0.86 | MAOA (0.37) | PARP1NOTUMTSHRCA12CA1 | |
| Methylamine SCHEMBL3886894 | 0.86 | MAOA (0.37) | PARP1NOTUMTSHRCA12CA1 | |
| Methyl Alcohol SCHEMBL3885098 | 0.86 | CA12 (0.37) | PARP1NOTUMTSHRCA12CA1 | |
| SCHEMBL5444154 | 0.86 | TRPM8 (0.35) | PARP1NOTUMTRPM8L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919814-A | Heterocyclic compounds | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |