Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 9/20 | 0.72 |
| ▸ | MMP2 | P08253 | 8/20 | 0.72 |
| ▸ | MMP13 | P45452 | 5/20 | 0.49 |
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308413 | 0.87 | MMP9 (0.95) | MMP9MMP2MMP13MMP1MMP8 | |
| SCHEMBL7308416 | 0.87 | MMP9 (0.95) | MMP9MMP2MMP13MMP1MMP8 | |
| SCHEMBL7305528 | 0.85 | MMP9 (1.00) | MMP9MMP2MMP13MMP1MMP8 | |
| SCHEMBL7305533 | 0.85 | MMP9 (1.00) | MMP9MMP2MMP13MMP1MMP8 | |
| SCHEMBL8524291 | 0.78 | MMP9 (0.68) | MMP9MMP2MMP13MMP1MMP3 | |
| SCHEMBL8483590 | 0.74 | MMP2 (0.55) | MMP9MMP2MMP1HPGDSMN1; SMN2 | |
| SCHEMBL7305247 | 0.74 | MMP9 (0.70) | MMP9MMP2MMP13MMP1MMP8 | |
| SCHEMBL27476403 | 0.74 | MMP9 (0.70) | MMP9MMP2MMP13MMP1MMP8 | |
| SCHEMBL8525263 | 0.74 | MMP9 (0.70) | MMP9MMP2MMP13MMP1MMP8 | |
| SCHEMBL27432261 | 0.74 | MMP9 (0.70) | MMP9MMP2MMP13MMP1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883131-A | Cyclic sulfone derivatives | PFIZER INC. (US) | 1999-03-16 | — | — | US | disclosed |