Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523943 | 0.80 | ALDH1A1 (0.34) | MAPTALDH1A1GSK3BRAB9ALMNA | |
| SCHEMBL16132462 | 0.76 | MAPT (0.46) | MAPTALDH1A1KIF11RAB9APKM | |
| SCHEMBL8524839 | 0.76 | MAPT (0.39) | MAPTALDH1A1KIF11GSK3BRAB9A | |
| SCHEMBL27076359 | 0.75 | ALDH1A1 (0.37) | P2RX7MAPTALDH1A1KIF11MAPK1 | |
| SCHEMBL7348087 | 0.71 | NPC1 (0.41) | MAPTALDH1A1CASP3CASP2CRBN | |
| SCHEMBL12559746 | 0.71 | TSHR (0.42) | MAPTALDH1A1LMNAMEN1TSHR | |
| SCHEMBL9366701 | 0.69 | PKM (0.41) | MAPTALDH1A1RAB9APKMSMN1; SMN2 | |
| SCHEMBL5467106 | 0.69 | MAPT (0.52) | MAPTALDH1A1GSK3BAKR1C4AKR1C3 | |
| SCHEMBL16110420 | 0.67 | MAPT (0.43) | MAPTALDH1A1KIF11RAB9APKM | |
| SCHEMBL5763044 | 0.67 | ALDH1A1 (0.32) | P2RX7MAPTALDH1A1MAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |