Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366701 | 0.92 | PKM (0.41) | MAPTALDH1A1PKMSMN1; SMN2RAB9A | |
| SCHEMBL29003189 | 0.86 | MAPK1 (0.40) | MAPTPKMAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL13417634 | 0.85 | EPHX2 (0.44) | MAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL5467106 | 0.78 | MAPT (0.52) | MAPTALDH1A1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL8525367 | 0.76 | SMN1; SMN2 (0.38) | MAPTALDH1A1SMN1; SMN2MEN1RAB9A | |
| SCHEMBL9372030 | 0.76 | SMYD3 (0.43) | MAPTALDH1A1PKMMAPK1 | |
| SCHEMBL8524437 | 0.76 | P2RX7 (0.38) | MAPTALDH1A1PKMAKR1C4AKR1C3 | |
| SCHEMBL9562601 | 0.75 | PKM (0.41) | MAPTALDH1A1PKMKIF11 | |
| SCHEMBL1024704 | 0.74 | CRBN (0.43) | ALDH1A1PKM | |
| SCHEMBL9371968 | 0.73 | RARB (0.43) | MAPTALDH1A1MAPK1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |