Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | RXRB | P28702 | 3/20 | 0.33 |
| ▸ | RXRG | P48443 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524437 | 0.80 | P2RX7 (0.38) | ALDH1A1RAB9ALMNAMAPK1HIF1A | |
| SCHEMBL8920419 | 0.71 | FLI1 (0.38) | ALDH1A1RAB9ALMNACRBNMAPT | |
| SCHEMBL8524839 | 0.71 | MAPT (0.39) | ALDH1A1RAB9ALMNAMAPK1GSK3B | |
| SCHEMBL17481990 | 0.71 | ALDH1A1 (0.44) | ALDH1A1MAPT | |
| SCHEMBL7350316 | 0.70 | NPC1 (0.41) | ALDH1A1RAB9ALMNAMAPK1HIF1A | |
| SCHEMBL158585 | 0.68 | CRBN (0.40) | ALDH1A1CRBNNPC1 | |
| SCHEMBL12559620 | 0.67 | CES1 (0.43) | CRBN | |
| SCHEMBL12567492 | 0.66 | ADRA1A (0.41) | ALDH1A1RAB9ALMNAMAPK1HIF1A | |
| SCHEMBL12559672 | 0.66 | CRBN (0.36) | ALDH1A1RAB9ALMNAMAPK1CRBN | |
| SCHEMBL5763044 | 0.65 | ALDH1A1 (0.32) | ALDH1A1MAPK1HIF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |