Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | FABP1 | P07148 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525044 | 0.94 | PKLR (0.49) | PKLRMEN1KMT2AEGLN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8524038 | 0.87 | F2 (0.56) | PKLRMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7358688 | 0.87 | PKLR (0.47) | PKLRMEN1KMT2AEGLN1ALDH1A1 | |
| SCHEMBL8524665 | 0.84 | SLC16A3 (0.42) | PKLRMEN1KMT2AEGLN1ALDH1A1 | |
| SCHEMBL8525755 | 0.82 | HSP90AA1 (0.49) | — | |
| Hydrochloric Acid SCHEMBL8525302 | 0.82 | F2 (0.56) | PKLRMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8525757 | 0.82 | KMT2A (0.44) | PKLRMEN1KMT2AEGLN1ALDH1A1 | |
| SCHEMBL8525447 | 0.81 | PKLR (0.44) | PKLR | |
| SCHEMBL7352541 | 0.77 | PKLR (0.48) | PKLRMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7353803 | 0.76 | PKLR (0.47) | PKLRMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999029670-A2 | AMINOCARBONYLTETRALIN AND DIHYDRONAPHTALENE DERIVATES AS THROMBIN INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-17 | — | — | WO | disclosed |