Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525044 | 0.86 | PKLR (0.49) | KMT2AMEN1EGLN1ALDH1A1GLO1 | |
| SCHEMBL8524454 | 0.82 | PKLR (0.49) | KMT2AMEN1EGLN1ALDH1A1PKLR | |
| SCHEMBL8524665 | 0.77 | SLC16A3 (0.42) | KMT2AMEN1EGLN1ALDH1A1PKLR | |
| SCHEMBL8489621 | 0.76 | EGLN1 (0.46) | EGLN1SMN1; SMN2ADORA2AADORA1NSD2 | |
| SCHEMBL8525447 | 0.74 | PKLR (0.44) | PKLR | |
| SCHEMBL7358688 | 0.73 | PKLR (0.47) | KMT2AMEN1EGLN1ALDH1A1PKLR | |
| Hydrochloric Acid SCHEMBL8525302 | 0.73 | F2 (0.56) | KMT2AMEN1ALDH1A1PKLR | |
| SCHEMBL8525436 | 0.72 | HDAC2 (0.50) | NSD2 | |
| SCHEMBL1320296 | 0.72 | HDAC2 (0.50) | ALDH1A1NSD2 | |
| SCHEMBL8494353 | 0.71 | HDAC2 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999029670-A2 | AMINOCARBONYLTETRALIN AND DIHYDRONAPHTALENE DERIVATES AS THROMBIN INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-17 | — | — | WO | disclosed |