Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6378390 | 0.84 | PTGS1 (0.56) | CCR2PTGS1PTGS2KEAP1NFE2L2 | |
| SCHEMBL8099526 | 0.80 | CYP19A1 (0.42) | CCR2PTGS1PTGS2HSD17B10TSHR | |
| SCHEMBL31090876 | 0.78 | PTGS1 (0.59) | CCR2PTGS1PTGS2HSD17B10TSHR | |
| SCHEMBL8524487 | 0.77 | PTGS2 (0.59) | CCR2PTGS1PTGS2MAPT | |
| SCHEMBL8524651 | 0.75 | MAPK1 (0.51) | CCR2PTGS1PTGS2KEAP1PIN1 | |
| SCHEMBL8099718 | 0.75 | PTGS1 (0.68) | CCR2PTGS1PTGS2PIN1TSHR | |
| SCHEMBL8737305 | 0.75 | HTR1A (0.55) | HTR1AHTR3ATSHRSMN1; SMN2SLC6A2 | |
| SCHEMBL13524349 | 0.75 | PTGS1 (0.65) | CCR2PTGS1PTGS2HSD17B10TSHR | |
| SCHEMBL8719438 | 0.74 | PTGS2 (0.68) | CCR2PTGS1PTGS2KEAP1HSD17B10 | |
| SCHEMBL31090806 | 0.74 | PTGS2 (0.50) | CCR2PTGS1PTGS2HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004948-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | NYCOMED AUSTRIA GMBH (AT) | 1999-12-21 | — | — | US | disclosed |