Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 17/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27561328 | 1.00 | TAS2R14 (0.57) | TAS2R14LMNACNR2MAPK1 | |
| SCHEMBL27485384 | 0.90 | TAS2R14 (0.48) | TAS2R14LMNACNR2MAPK1 | |
| SCHEMBL8524401 | 0.90 | TAS2R14 (0.48) | TAS2R14LMNACNR2MAPK1 | |
| Bicarbonate SCHEMBL9058314 | 0.88 | PTGES (0.48) | TAS2R14LMNACNR2 | |
| SCHEMBL16558052 | 0.76 | MAPK1 (0.51) | MAPK1 | |
| SCHEMBL6774597 | 0.73 | TAS2R14 (0.47) | TAS2R14MAPK1 | |
| SCHEMBL1279003 | 0.73 | TAS2R14 (1.00) | TAS2R14LMNA | |
| SCHEMBL1279268 | 0.73 | TAS2R14 (1.00) | TAS2R14LMNAMAPK1 | |
| SCHEMBL1133773 | 0.72 | LMNA (0.59) | LMNA | |
| SCHEMBL12077868 | 0.71 | TAS2R14 (0.52) | TAS2R14LMNACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922717-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| CN-1183770-A | Piperazine derivatives, medicaments containing these compounds, their use and processes for their preparation | THOMAE GMBH DR K (DE) | 1998-06-03 | — | — | CN | disclosed |