Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.43 |
| ▸ | RARB | P10826 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957300 | 0.95 | HSD11B1 (0.47) | HSD11B1RARBALDH1A1MAPTMEN1 | |
| SCHEMBL6949197 | 0.95 | HSD11B1 (0.47) | HSD11B1RARBALDH1A1MAPTMEN1 | |
| SCHEMBL6953051 | 0.90 | HSD11B1 (0.47) | HSD11B1TP53AGTR1RAB9ASMN1; SMN2 | |
| SCHEMBL6956381 | 0.86 | CA2 (0.36) | HSD11B1EGFRAGTR1 | |
| SCHEMBL1773521 | 0.86 | FYN (0.39) | AGTR1 | |
| SCHEMBL6960893 | 0.85 | CA2 (0.35) | HSD11B1EGFRAGTR1 | |
| SCHEMBL6961100 | 0.85 | NPC1 (0.39) | MAPTAGTR1RAB9A | |
| SCHEMBL6949584 | 0.83 | LTA4H (0.37) | HSD11B1AGTR1 | |
| SCHEMBL9709732 | 0.83 | LTB4R2 (0.41) | CYP3A4AGTR1 | |
| SCHEMBL6956844 | 0.83 | GP6 (0.35) | HSD11B1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874593-A | SULFUR CONTAINING AMIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |