SCHEMBL8524558

SCHEMBL8524558

Fc1cccc(-c2ccc(Cl)cc2Br)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 1/20 0.43
THRB P10828 1/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43
GABRA3 P34903 1/20 0.43
GABRA2 P47869 1/20 0.43
GABRB2 P47870 1/20 0.43
GABRA4 P48169 1/20 0.43
GABRE P78334 1/20 0.43
GABRA6 Q16445 1/20 0.43
GABRG1 Q8N1C3 1/20 0.43
GABRG3 Q99928 1/20 0.43
GABRQ Q9UN88 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23606014 0.86 GABRP (0.42) MEN1KMT2AGABRPGABRDGABRA1
SCHEMBL20687339 0.85 TDO2 (0.43) MEN1KMT2APIK3CATAAR1ESR2
SCHEMBL20898215 0.81 CNR1 (0.51) MEN1KMT2AALDH1A1THRBGABRP
SCHEMBL20687344 0.81 MEN1 (0.44) MEN1KMT2AALDH1A1GABRPGABRD
SCHEMBL31067089 0.81 CNR1 (0.51) MEN1KMT2AALDH1A1THRBGABRP
SCHEMBL20898099 0.79 MEN1 (0.46) MEN1KMT2AALDH1A1THRBGABRP
SCHEMBL31067143 0.79 MEN1 (0.46) MEN1KMT2AALDH1A1THRBGABRP
SCHEMBL26179587 0.79 NPC1 (0.46) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL571071 0.79 ALDH1A1 (0.54) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL21102581 0.79 ALDH1A1 (0.35) MEN1KMT2AALDH1A1GABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5985919-A INSECTICIDES AND FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-11-16 US disclosed