SCHEMBL8524644

SCHEMBL8524644

c1c[nH]c(SN2CCCCC2)n1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.36
TXN P10599 1/20 0.35
TXNRD1 Q16881 1/20 0.35
GRIN2B Q13224 2/20 0.33
FDPS P14324 1/20 0.33
KCNH2 Q12809 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
GRIN2A Q12879 1/20 0.32
ALDH1A1 P00352 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MGLL Q99685 1/20 0.31
CTSK P43235 1/20 0.31
KCNA5 P22460 3/20 0.31
KCNE1 P15382 1/20 0.31
HSD11B1 P28845 1/20 0.30
JAK3 P52333 1/20 0.30
F2RL1 P55085 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8025969 0.98 ALOX15 (0.37) ALOX15TXNTXNRD1GRIN2BFDPS
SCHEMBL24550622 0.67 SMN1; SMN2 (0.55) ALDH1A1SMN1; SMN2HPGDHSD17B10
SCHEMBL3503342 0.67 TXN (0.55) ALOX15TXNTXNRD1GRIN2BFDPS
SCHEMBL1740306 0.67 TXN (0.45) ALOX15TXNTXNRD1GRIN2BFDPS
SCHEMBL311710 0.65 BCHE (0.42) ALOX15KCNH2HRH3ALDH1A1SMN1; SMN2
SCHEMBL12949681 0.65 CTSK (0.36) TXNTXNRD1GRIN2BFDPSGRIN2A
Hydrochloric Acid SCHEMBL29375122 0.64 BCHE (0.41) ALOX15KCNH2HRH3ALDH1A1SMN1; SMN2
SCHEMBL25570 0.63
SCHEMBL7658749 0.63
SCHEMBL1145987 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5965537-A ANTICANCER AGENTS; WATER SOLUBILITY BASF AKTIENGESELLSCHAFT (DE) 1999-10-12 US disclosed