Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525364 | 0.83 | L3MBTL1 (0.44) | KMT2AGAAPKMMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8523964 | 0.82 | PDE5A (0.43) | KMT2AGAAMAPTL3MBTL1KDM4E | |
| SCHEMBL8526091 | 0.80 | NPC1 (0.50) | KMT2AMEN1GAAMAPTL3MBTL1 | |
| SCHEMBL8524721 | 0.78 | L3MBTL1 (0.46) | KMT2AMEN1GAAPKMMAPT | |
| SCHEMBL11137884 | 0.72 | NPC1 (0.51) | KMT2AMEN1MAPTL3MBTL1KDM4E | |
| SCHEMBL8525541 | 0.71 | SMN1; SMN2 (0.47) | KMT2AGAAPKMMAPTL3MBTL1 | |
| SCHEMBL8525159 | 0.70 | LMNA (0.49) | KMT2AMEN1GAAMAPTL3MBTL1 | |
| SCHEMBL1053453 | 0.70 | KMT2A (0.60) | KMT2AMEN1GAAMAPTL3MBTL1 | |
| SCHEMBL8314849 | 0.69 | NPC1 (0.52) | KMT2AMEN1PKMMAPTL3MBTL1 | |
| SCHEMBL27543185 | 0.68 | POLB (0.62) | KMT2AMEN1GAAPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007352-A2 | METHOD FOR PROMOTING EXPRESSION OF LDL RECEPTOR GENE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-02-18 | — | — | WO | claimed |
| WO-1999007352-A2 | METHOD FOR PROMOTING EXPRESSION OF LDL RECEPTOR GENE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-02-18 | — | — | WO | disclosed |