Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CBFB | Q13951 | 3/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | GPR39 | O43194 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525157 | 0.78 | LMNA (0.54) | LMNAHTTL3MBTL1NPC1TDP1 | |
| SCHEMBL8045470 | 0.77 | NPC1 (0.47) | LMNAHTTL3MBTL1NPC1TDP1 | |
| SCHEMBL8525364 | 0.73 | L3MBTL1 (0.44) | LMNAHTTL3MBTL1NPC1TDP1 | |
| Hydrochloric Acid SCHEMBL8523964 | 0.72 | PDE5A (0.43) | LMNAHTTL3MBTL1NPC1TDP1 | |
| SCHEMBL8525541 | 0.71 | SMN1; SMN2 (0.47) | LMNAHTTL3MBTL1NPC1TDP1 | |
| SCHEMBL11131683 | 0.71 | NPC1 (0.53) | LMNAHTTL3MBTL1NPC1TDP1 | |
| SCHEMBL11136903 | 0.71 | NPC1 (0.49) | LMNAHTTL3MBTL1NPC1TDP1 | |
| SCHEMBL8524726 | 0.70 | KMT2A (0.53) | LMNAHTTL3MBTL1NPC1TDP1 | |
| SCHEMBL11132901 | 0.69 | HTT (0.46) | LMNAHTTL3MBTL1NPC1TDP1 | |
| SCHEMBL11288499 | 0.68 | NPY5R (0.57) | LMNAHTTL3MBTL1NPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007352-A2 | METHOD FOR PROMOTING EXPRESSION OF LDL RECEPTOR GENE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-02-18 | — | — | WO | claimed |