Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | KRAS | P01116 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525906 | 0.78 | HTT (0.50) | SMN1; SMN2HTTL3MBTL1LMNAKDM4E | |
| SCHEMBL8525373 | 0.77 | HTT (0.46) | SMN1; SMN2HTTL3MBTL1LMNAKDM4E | |
| SCHEMBL11655439 | 0.76 | L3MBTL1 (0.60) | SMN1; SMN2HTTL3MBTL1LMNAKDM4E | |
| SCHEMBL11652255 | 0.76 | ALDH1A1 (0.49) | SMN1; SMN2HTTL3MBTL1LMNAKDM4E | |
| SCHEMBL8525364 | 0.75 | L3MBTL1 (0.44) | SMN1; SMN2HTTL3MBTL1LMNAKDM4E | |
| SCHEMBL8525540 | 0.74 | NPC1 (0.50) | SMN1; SMN2HTTL3MBTL1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL8523964 | 0.74 | PDE5A (0.43) | SMN1; SMN2HTTL3MBTL1LMNAKDM4E | |
| SCHEMBL5730778 | 0.73 | HTT (0.45) | SMN1; SMN2HTTL3MBTL1LMNAKDM4E | |
| SCHEMBL5916410 | 0.73 | ALDH1A1 (0.44) | SMN1; SMN2HTTL3MBTL1LMNAKDM4E | |
| SCHEMBL5478697 | 0.73 | KDM4E (0.59) | SMN1; SMN2HTTL3MBTL1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007352-A2 | METHOD FOR PROMOTING EXPRESSION OF LDL RECEPTOR GENE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-02-18 | — | — | WO | claimed |
| WO-1999007352-A2 | METHOD FOR PROMOTING EXPRESSION OF LDL RECEPTOR GENE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-02-18 | — | — | WO | disclosed |