Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 13/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 10/20 | 0.36 |
| ▸ | RXRB | P28702 | 9/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 3/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.35 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9371968 | 0.87 | RARB (0.43) | SMN1; SMN2RXRAMAPTALDH1A1RXRG | |
| SCHEMBL8524419 | 0.81 | ALDH1A1 (0.49) | SMN1; SMN2MAPTALDH1A1RARARARB | |
| SCHEMBL9366701 | 0.79 | PKM (0.41) | SMN1; SMN2MAPTALDH1A1HDAC3HDAC4 | |
| SCHEMBL8524839 | 0.76 | MAPT (0.39) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL13417634 | 0.74 | EPHX2 (0.44) | SMN1; SMN2MAPTALDH1A1HDAC6 | |
| SCHEMBL5766655 | 0.74 | RARB (0.41) | RXRAMAPTALDH1A1RARBRARG | |
| SCHEMBL9366243 | 0.70 | ALDH1A1 (0.38) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8523897 | 0.67 | MMP12 (0.45) | SMN1; SMN2MAPTALDH1A1RARBRARG | |
| SCHEMBL15304426 | 0.67 | CYP3A4 (0.50) | MAPTALDH1A1METMEN1KMT2A | |
| SCHEMBL6450714 | 0.67 | HDAC3 (0.56) | SMN1; SMN2MAPTALDH1A1RARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |