Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NEK2 | P51955 | 3/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524419 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPTNEK2CDK1CCNB1 | |
| SCHEMBL7417490 | 0.76 | PGR (0.50) | ALDH1A1MAPT | |
| SCHEMBL5467106 | 0.75 | MAPT (0.52) | ALDH1A1MAPTKDM4ECRBNNPC1 | |
| SCHEMBL1145012 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MAPTCRBNL3MBTL1NPC1 | |
| SCHEMBL6450714 | 0.74 | HDAC3 (0.56) | ALDH1A1MAPTNEK2CDK1CCNB1 | |
| SCHEMBL26406342 | 0.73 | PDE7A (0.49) | PDE7A | |
| SCHEMBL8524452 | 0.70 | PDE7A (0.50) | ALDH1A1MAPTLMNACRBNNPC1 | |
| SCHEMBL1304506 | 0.70 | EPHX2 (0.59) | ALDH1A1MAPTGRIN2BSMYD3 | |
| SCHEMBL5479280 | 0.70 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4ECRBNHDAC3 | |
| SCHEMBL5680486 | 0.69 | PGR (0.50) | ALDH1A1MAPTNEK2KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |