Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544920 | 0.82 | TDP1 (0.48) | ELANEMAPTALDH1A1KDM4EATM | |
| SCHEMBL9035573 | 0.81 | MAPT (0.46) | ELANEMAPTALDH1A1CYP1A2KDM4E | |
| SCHEMBL10751774 | 0.79 | TDP1 (0.42) | ELANEMAPTALDH1A1KDM4EATM | |
| SCHEMBL10411906 | 0.78 | TDP1 (0.45) | ELANEMAPTALDH1A1KDM4EATM | |
| SCHEMBL28008692 | 0.77 | PTGS2 (0.42) | MAPTKDM4EATML3MBTL1PTGS2 | |
| SCHEMBL16672480 | 0.77 | POLB (0.45) | MAPTALDH1A1ATML3MBTL1NPC1 | |
| SCHEMBL27720206 | 0.76 | TDP1 (0.44) | ELANEMAPTALDH1A1KDM4EATM | |
| SCHEMBL29211141 | 0.76 | TDP1 (0.44) | ELANEMAPTALDH1A1KDM4EATM | |
| SCHEMBL27921525 | 0.76 | CYP1A2 (0.40) | ELANEMAPTALDH1A1CYP1A2ATM | |
| SCHEMBL16713297 | 0.76 | L3MBTL1 (0.51) | MAPTALDH1A1CYP1A2KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903866-A | Polyvinyl alcohol modified multifunctional powder slump retaining agent and preparation method thereof | 江苏奥莱特新材料股份有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-111285751-B | Method for preparing alkene compound from alkyne compound | 中国科学院化学研究所 | 2021-06-01 | — | — | CN | claimed |
| CN-111285751-A | Method for preparing alkene compound from alkyne compound | 中国科学院化学研究所 | 2020-06-16 | — | — | CN | claimed |
| CN-103788137-B | Ferrocene piperidones compounds and preparation method thereof | NANKAI UNIVERSITY (CN) | 2016-05-11 | — | — | CN | claimed |
| CN-103788137-A | Ferrocene piperidones compound and preparation method thereof | UNIV NANKAI | 2014-05-14 | — | — | CN | claimed |
| CN-119841797-A | 3-Arylation/3-alkenylation coumarin compound, preparation method and application thereof | 云南民族大学 | 2025-04-18 | — | — | CN | disclosed |
| CN-116217928-B | Pyridazinone group-containing high-molecular organic polymer material and preparation method and application thereof | 齐鲁工业大学(山东省科学院) | 2025-01-28 | — | — | CN | disclosed |
| CN-116217928-A | Pyridazinone group-containing high-molecular organic polymer material and preparation method and application thereof | 齐鲁工业大学(山东省科学院) | 2023-06-06 | — | — | CN | disclosed |
| CN-111423299-B | Photochemical catalytic synthesis method of aryl olefin compound | 北京工商大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-114568026-A | Additive organopolysiloxane composition, curable composition, and film | 美国陶氏有机硅公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-113121427-B | Quinoline derivative and preparation method and application thereof | 广东工业大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-110168032-B | Curable compositions and coated substrates | 美国陶氏有机硅公司 | 2021-08-17 | — | — | CN | disclosed |
| EP-0579769-A1 | 2- AND 5-ALKYL AND PHENYL SUBSTITUTED 4-(1-HYDROXY, 1-ACYLOXY OR 1-CARBAMOYLOXY)-5-HYDROXY-2(5H)-FURANONES AS ANTI-INFLAMMATORY AGENTS | ALLERGAN, INC. (US) | 1994-01-26 | — | — | EP | disclosed |
| US-5268387-A | Containing ester or carbamate group | ALLERGAN, INC. (US) | 1993-12-07 | — | — | US | disclosed |
| WO-1993021915-A1 | PHARMACEUTICAL COMPOSITIONS FOR INHIBITING BONE LOSS CONTAINING 3 AND 4-SUBSTITUTED 2(5H)-FURANONES | ALLERGAN, INC. (US) | 1993-11-11 | — | — | WO | disclosed |
| US-5183906-A | Antibody inhibitors, antiarthritic agents, antiallergens | ALLERGAN, INC. (US) | 1993-02-02 | — | — | US | disclosed |
| US-5171863-A | 2-trialkylsily-4-substituted furan derivatives | ALLERGAN, INC. (US) | 1992-12-15 | — | — | US | disclosed |
| WO-1992019610-A1 | 2- AND 5-ALKYL AND PHENYL SUBSTITUTED 4-(1-HYDROXY, 1-ACYLOXY OR 1-CARBAMOYLOXY)-5-HYDROXY-2(5H)-FURANONES AS ANTI-INFLAMMATORY AGENTS | ALLERGAN, INC. (US) | 1992-11-12 | — | — | WO | disclosed |
| US-5082954-A | Intermediates and processes for preparing 4-substituted 2-5(H)-furanones as anti-inflammatory agents | ALLERGAN, INC. (US) | 1992-01-21 | — | — | US | disclosed |
| US-4123532-A | ADMINISTERING A PYRAZOLO(1,5-C)QUINAZOLIN-5(6H)-ONE COMPOUND | E. R. SQUIBB & SONS, INC. (US) | 1978-10-31 | — | — | US | disclosed |