Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887757 | 0.84 | RAB9A (0.75) | RAB9AHTTALDH1A1MEN1KMT2A | |
| SCHEMBL7408274 | 0.83 | RAB9A (0.66) | RAB9AHTTALDH1A1MEN1KMT2A | |
| SCHEMBL1104176 | 0.81 | RAB9A (0.76) | RAB9AHTTALDH1A1MEN1KMT2A | |
| SCHEMBL31323285 | 0.81 | RAB9A (0.71) | RAB9AHTTALDH1A1MEN1KMT2A | |
| SCHEMBL8839293 | 0.78 | RAB9A (0.81) | RAB9AHTTALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29463388 | 0.78 | RAB9A (0.70) | RAB9AHTTALDH1A1MEN1KMT2A | |
| SCHEMBL4923105 | 0.77 | MAPT (0.69) | RAB9AALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL12199536 | 0.77 | RAB9A (0.69) | RAB9AHTTALDH1A1MEN1KMT2A | |
| SCHEMBL9422337 | 0.77 | SMN1; SMN2 (0.73) | RAB9AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6373144 | 0.76 | MAPT (0.59) | RAB9AHTTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008243-A | AN ENZYME INHIBITOR FOR PREVENTING THE DEGRADATION AND REMODELING OF CONNECTIVE TISSUES | AGOURON PHARMACEUTICALS, INC. (US) | 1999-12-28 | — | — | US | disclosed |