Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | F12 | P00748 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8523960 | 0.86 | NPC1 (0.46) | L3MBTL1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL8524721 | 0.83 | L3MBTL1 (0.46) | L3MBTL1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL8524927 | 0.78 | NPC1 (0.50) | L3MBTL1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL8525364 | 0.76 | L3MBTL1 (0.44) | L3MBTL1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL8525540 | 0.75 | NPC1 (0.50) | L3MBTL1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL8525157 | 0.74 | LMNA (0.54) | L3MBTL1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL5789993 | 0.70 | L3MBTL1 (0.66) | L3MBTL1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL8524775 | 0.69 | NPC1 (0.63) | L3MBTL1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL8525904 | 0.68 | NPC1 (0.54) | L3MBTL1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL12955341 | 0.67 | AR (0.77) | PRMT5LMNAPARP1ENPP1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007352-A2 | METHOD FOR PROMOTING EXPRESSION OF LDL RECEPTOR GENE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-02-18 | — | — | WO | claimed |
| WO-1999007352-A2 | METHOD FOR PROMOTING EXPRESSION OF LDL RECEPTOR GENE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-02-18 | — | — | WO | disclosed |