Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | F12 | P00748 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18112556 | 0.80 | NPC1 (0.55) | NPC1RAB9AL3MBTL1SMN1; SMN2ALPL | |
| SCHEMBL8525904 | 0.79 | NPC1 (0.54) | NPC1RAB9AL3MBTL1SMN1; SMN2ALPL | |
| SCHEMBL8525369 | 0.77 | NPC1 (0.49) | NPC1RAB9AL3MBTL1SMN1; SMN2ALPL | |
| SCHEMBL8525362 | 0.75 | L3MBTL1 (0.47) | NPC1RAB9AL3MBTL1SMN1; SMN2ALPL | |
| Hydrochloric Acid SCHEMBL8523960 | 0.74 | NPC1 (0.46) | NPC1RAB9AL3MBTL1SMN1; SMN2ALPL | |
| SCHEMBL8525541 | 0.74 | SMN1; SMN2 (0.47) | NPC1RAB9AL3MBTL1SMN1; SMN2PKM | |
| SCHEMBL8524721 | 0.72 | L3MBTL1 (0.46) | NPC1RAB9AL3MBTL1SMN1; SMN2ALPL | |
| SCHEMBL8525157 | 0.72 | LMNA (0.54) | NPC1RAB9AL3MBTL1SMN1; SMN2ALPL | |
| SCHEMBL8524775 | 0.71 | NPC1 (0.63) | NPC1RAB9AL3MBTL1SMN1; SMN2ALPL | |
| SCHEMBL2003184 | 0.70 | NPC1 (0.66) | NPC1RAB9AL3MBTL1SMN1; SMN2ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007352-A2 | METHOD FOR PROMOTING EXPRESSION OF LDL RECEPTOR GENE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-02-18 | — | — | WO | claimed |
| WO-1999007352-A2 | METHOD FOR PROMOTING EXPRESSION OF LDL RECEPTOR GENE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-02-18 | — | — | WO | disclosed |