Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | MMP2 | P08253 | 1/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.68 |
| ▸ | COMT | P21964 | 1/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | METAP2 | P50579 | 1/20 | 0.68 |
| ▸ | METAP1 | P53582 | 1/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.63 |
| ▸ | ERN1 | O75460 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxyquinoline SCHEMBL28191778 | 0.84 | TSHR (0.95) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL28459062 | 0.83 | MMP2 (0.84) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL12492889 | 0.82 | TSHR (0.91) | TSHRMMP2CHRM1COMTADRA1A | |
| SCHEMBL13474692 | 0.82 | TSHR (0.83) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL29365411 | 0.82 | TSHR (1.00) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL29716519 | 0.82 | TSHR (1.00) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL37189 | 0.82 | TSHR (1.00) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL253313 | 0.82 | TSHR (1.00) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL27638395 | 0.81 | TSHR (0.88) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL23522696 | 0.80 | TSHR (0.95) | TSHRMMP2CHRM1COMTADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |