Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566733 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL6802264 | 0.80 | BCAT2 (0.42) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL28052100 | 0.77 | DAO (0.45) | TLR7KMT2ATSHRMEN1 | |
| SCHEMBL29115280 | 0.76 | HPGD (0.60) | ALDH1A1HPGDMAPTTLR7CYP3A4 | |
| SCHEMBL319866 | 0.76 | KMT2A (0.73) | ALDH1A1HPGDMAPTCYP3A4KDM4E | |
| SCHEMBL10696215 | 0.76 | HSP90AA1 (0.43) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL11785182 | 0.75 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL6243233 | 0.75 | KMT2A (0.55) | ALDH1A1HPGDMAPTTLR7CYP3A4 | |
| SCHEMBL1944831 | 0.75 | ALDH1A1 (0.63) | ALDH1A1HPGDMAPTTLR7CYP3A4 | |
| SCHEMBL9756675 | 0.74 | ALDH1A1 (0.49) | ALDH1A1CYP3A4KDM4EKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919732-A | Herbicidal 3-arylamino-6-trifluoromethyluracils | HOECHST SCHERING AGREVO GMBH (DE) | 1999-07-06 | — | — | US | disclosed |
| WO-1998034924-A1 | HERBICIDAL 3-ARYLAMINO-6-TRIFLUOROMETHYL URACYLS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-08-13 | — | — | WO | disclosed |