Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.43 |
| ▸ | TRAP1 | Q12931 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 7/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237639 | 0.83 | MAOB (0.44) | KMT2ABCAT2BCAT1 | |
| SCHEMBL8820735 | 0.77 | ALDH1A1 (0.43) | HSP90AA1HSP90B1TRAP1KMT2AKDM4E | |
| SCHEMBL6802264 | 0.77 | BCAT2 (0.42) | HSP90AA1HSP90B1TRAP1KMT2AKDM4E | |
| SCHEMBL8525560 | 0.76 | ALDH1A1 (0.50) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL29574224 | 0.76 | BCAT1 (0.54) | ALDH1A1BCAT2BCAT1 | |
| SCHEMBL8691597 | 0.76 | BCAT1 (0.54) | ALDH1A1BCAT2BCAT1 | |
| SCHEMBL8924655 | 0.73 | MKNK1 (0.39) | HSP90AA1HSP90B1TRAP1KDM4EALDH1A1 | |
| SCHEMBL8818440 | 0.73 | BCAT1 (0.50) | KDM4EALDH1A1DDR1BCAT2BCAT1 | |
| SCHEMBL7471937 | 0.72 | BCAT1 (0.40) | KMT2AKDM4EALDH1A1DDR1BCAT2 | |
| SCHEMBL6966995 | 0.71 | BCAT1 (0.50) | KDM4EALDH1A1BCAT2BCAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255047-A1 | 3-Aryl uraciles and their use as herbicides | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | disclosed |