Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.46 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525560 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL4762572 | 0.81 | ALDH1A1 (0.63) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL7556878 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KMT2ABCAT2BCAT1SMN1; SMN2 | |
| SCHEMBL8612009 | 0.77 | BCAT2 (0.41) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL8612850 | 0.76 | BCAT2 (0.40) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL27174639 | 0.75 | RGS4 (0.49) | ALDH1A1KMT2AMAPTMEN1P2RX4 | |
| SCHEMBL30999955 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL8570267 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL8612943 | 0.74 | BCAT2 (0.37) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL8818440 | 0.74 | BCAT1 (0.50) | ALDH1A1MAPTKDM4EBCAT2BCAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4305033-A1 | TRICYCLIC PESTICIDAL COMPOUNDS | BASF SE (DE) | 2024-01-17 | — | — | EP | disclosed |
| CN-110546152-B | Bicyclic pesticide compounds | 巴斯夫欧洲公司 | 2023-09-08 | — | — | CN | disclosed |
| WO-2022189189-A1 | TRICYCLIC PESTICIDAL COMPOUNDS | BASF SE (DE) | 2022-09-15 | — | — | WO | disclosed |
| CN-110546152-A | Bicyclic pesticidal compounds | BASF SE | 2019-12-06 | — | — | CN | disclosed |
| EP-3436457-A1 | BICYCLIC COMPOUNDS | BASF SE (DE) | 2019-02-06 | — | — | EP | disclosed |
| CN-108779121-A | Dicyclic compound | 巴斯夫欧洲公司 | 2018-11-09 | — | — | CN | disclosed |
| WO-2017167832-A1 | BICYCLIC COMPOUNDS | BASF SE (DE) | 2017-10-05 | — | — | WO | disclosed |
| US-5780630-A | 1-METHYL-6-TRIFLUOROMETHYL-2,4(1H,3H)PYRIMIDINEDIONE AS AN INTERMEDIATE FOR HERBICIDES E.G. 1-METHYL-6-TRIFLUOROMETHYL-3-(4-METHOXYPHENYLMETHYL) -2,4(1H,3H)PYRIMIDINEDIONE | FMC CORPORATION (US) | 1998-07-14 | — | — | US | disclosed |
| WO-1998008824-A1 | AN INTERMEDIATE USEFUL IN THE SYNTHESIS OF PESTICIDAL URACILS | FMC CORPORATION (US) | 1998-03-05 | — | — | WO | disclosed |