Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525868 | 0.89 | LMNA (0.37) | LMNAPOLBHCRTR1HCRTR2MLYCD | |
| SCHEMBL8524334 | 0.87 | HCRTR2 (0.43) | HCRTR1MAPTHCRTR2MLYCDPTGDR2 | |
| SCHEMBL8524086 | 0.85 | NR1H4 (0.40) | LMNAPOLBHCRTR1HCRTR2HTT | |
| SCHEMBL8524250 | 0.85 | LMNA (0.37) | LMNAPOLBHCRTR1MAPTHCRTR2 | |
| SCHEMBL8817056 | 0.84 | MLYCD (0.41) | LMNAPOLBMAPTMLYCDPTGDR2 | |
| SCHEMBL8525222 | 0.84 | HCRTR2 (0.36) | LMNAHCRTR1MAPTHCRTR2HTT | |
| SCHEMBL8488086 | 0.83 | MLYCD (0.40) | LMNAPOLBMAPTMLYCDPTGDR2 | |
| SCHEMBL8524835 | 0.83 | HCRTR2 (0.34) | LMNAHCRTR1MAPTHCRTR2HTT | |
| SCHEMBL8525068 | 0.83 | HCRTR2 (0.35) | LMNAHCRTR1MAPTHCRTR2HTT | |
| SCHEMBL8490879 | 0.82 | ALDH1A1 (0.38) | LMNAHCRTR1MAPTHCRTR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |