Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
| ▸ | MC1R | Q01726 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGAV | P06756 | 2/20 | 0.44 |
| ▸ | NPY1R | P25929 | 3/20 | 0.44 |
| ▸ | NPY4R | P50391 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | FURIN | P09958 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526187 | 0.84 | MCHR1 (0.60) | MC4RMC3RMC1RNPY1RNPY4R | |
| SCHEMBL7750688 | 0.80 | MCHR1 (0.59) | NPY1RNPY4RNPY5RMCHR1FURIN | |
| SCHEMBL1803249 | 0.79 | SIRT5 (0.54) | HDAC1HDAC2 | |
| SCHEMBL7260360 | 0.79 | PTGER4 (0.52) | CTSLCTSSPTGER4TPSAB1ITGB3 | |
| SCHEMBL8525686 | 0.79 | NPY1R (0.52) | NPY1RNPY4RNPY5R | |
| SCHEMBL8525723 | 0.79 | TGM2 (0.39) | TGM2MC4RMC3RMC1RPRSS1 | |
| SCHEMBL8126906 | 0.77 | PTGER4 (0.51) | TGM2CTSLCTSSCTSBPTGER4 | |
| SCHEMBL8525943 | 0.77 | MCHR1 (0.59) | MC4RMC3RMC1RNPY1RMCHR1 | |
| SCHEMBL24838023 | 0.77 | CA1 (0.58) | CTSLCTSSPTGER4TPSAB1SMN1; SMN2 | |
| SCHEMBL13389079 | 0.77 | CTSL (0.61) | CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |