Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 4/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.38 |
| ▸ | RELA | Q04206 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL968867 | 1.00 | NFKB1 (0.38) | NFKB1NFKB2RELA | |
| SCHEMBL968866 | 1.00 | NFKB1 (0.38) | NFKB1NFKB2RELA | |
| SCHEMBL2953173 | 0.83 | NFKB1 (0.30) | NFKB1NFKB2RELA | |
| SCHEMBL4417335 | 0.83 | NFKB1 (0.30) | NFKB1NFKB2RELA | |
| SCHEMBL5613785 | 0.83 | NFKB1 (0.30) | NFKB1NFKB2RELA | |
| SCHEMBL3449840 | 0.81 | NFKB1 (0.37) | NFKB1NFKB2RELA | |
| SCHEMBL5634238 | 0.81 | NFKB1 (0.37) | NFKB1NFKB2RELA | |
| SCHEMBL13734264 | 0.76 | NLRP3 (0.39) | NFKB1NFKB2RELA | |
| SCHEMBL15007568 | 0.75 | — | — | |
| SCHEMBL8577970 | 0.73 | NFKB1 (0.46) | NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013620-A1 | Process for the peparation of 4-hydroxycyclopent-2-enone and derivatives | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 1980-07-23 | — | — | EP | claimed |
| US-4132726-A | INTERMEDIATES FOR PROSTAGLANDIN COMPOUNDS | TEIJIN LIMITED (JP) | 1979-01-02 | — | — | US | claimed |
| CN-118162116-B | Preparation method and application of membrane-encapsulated fiber array oxide microreactor | 南京师范大学 | 2026-05-15 | — | — | CN | disclosed |
| CN-118162116-A | Preparation method and application of membrane-encapsulated fiber array oxide microreactor | 南京师范大学 | 2024-06-11 | — | — | CN | disclosed |
| EP-3452485-A2 | ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | Oncoarendi Therapeutics SA (PL) | 2019-03-13 | — | — | EP | disclosed |
| WO-2017191130-A2 | ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | ONCOARENDI THERAPEUTICS SA (PL) | 2017-11-09 | — | — | WO | disclosed |
| EP-1537066-B1 | CYCLOPENTENONE DERIVATIVES AS POTENT ACTIVATORS OF HSF-1 | BIOGEM S C AR L (IT) | 2017-01-25 | — | — | EP | disclosed |
| EP-2433941-A1 | Process for isolating the antiviral agent [1S-(1alpha, 3alpha, 4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one | Bristol-Myers Squibb Company (US) | 2012-03-28 | — | — | EP | disclosed |
| US-7759399-B2 | Pharmaceutical compositions | CRAWFORD HEALTHCARE HOLDINGS LIMITED (GB) | 2010-07-20 | — | — | US | disclosed |
| US-7550619-B2 | Intermediates in the preparation of the antiviral agent [1S-(1α, 3α, 4β)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxmethyl)-2-methylenecyclopentyl]-6H-purin-6-one | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-06-23 | — | — | US | disclosed |
| US-7541460-B2 | Process for preparing the antiviral agent [1S-(1alpha, 3alpha, 4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-3-methylenecyclopentyl]-6H-purin-6-one | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-06-02 | — | — | US | disclosed |
| WO-2001032655-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2001-05-10 | — | — | WO | disclosed |
| US-6177586-B1 | USEFUL AS A PHARMACEUTICAL SUCH AS AN AGENT FOR PROMOTING BONE FORMATION, AN AGENT FOR SUPPRESSING PROLIFERATION OF TUMOR CELLS, AN AGENT FOR HIGH CALCIUM BLOOD DISEASES, AND AN IMMUNOSUPPRESSION AGENT | TEIJIN LIMITED (JP) | 2001-01-23 | — | — | US | disclosed |
| US-5986112-A | STEROID DERIVATIVES AS ANTITUMOR AGENTS AND BLOOD METAL CONCENTRATES | TEIJIN LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0854138-A2 | Vitamin D3 derivative and production process thereof | TEIJIN LIMITED (JP) | 1998-07-22 | — | — | EP | disclosed |
| EP-0854139-A2 | Vitamin D3 derivative and production process thereof | TEIJIN LIMITED (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5719297-A | Vitamin D3 derivatives and production process thereof | TEIJIN LIMITED (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0712843-A1 | VITAMIN D3 DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1996-05-22 | — | — | EP | disclosed |
| EP-0013620-A1 | Process for the peparation of 4-hydroxycyclopent-2-enone and derivatives | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 1980-07-23 | — | — | EP | disclosed |
| US-4132726-A | INTERMEDIATES FOR PROSTAGLANDIN COMPOUNDS | TEIJIN LIMITED (JP) | 1979-01-02 | — | — | US | disclosed |