Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 1.00 |
| ▸ | DRD2 | P14416 | 8/20 | 0.89 |
| ▸ | DRD4 | P21917 | 8/20 | 0.89 |
| ▸ | DRD3 | P35462 | 8/20 | 0.89 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526596 | 0.86 | SIGMAR1 (0.75) | SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL8120171 | 0.84 | SIGMAR1 (0.93) | SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL8117971 | 0.83 | SIGMAR1 (1.00) | SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL6956820 | 0.79 | SIGMAR1 (0.73) | SIGMAR1DRD4SLC6A12 | |
| SCHEMBL10107601 | 0.79 | SLC6A12 (0.83) | SIGMAR1DRD2DRD4DRD3SLC6A12 | |
| SCHEMBL8119272 | 0.78 | SIGMAR1 (0.82) | SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL8111456 | 0.78 | SIGMAR1 (0.80) | SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL6109825 | 0.76 | DRD4 (0.76) | SIGMAR1DRD2DRD4DRD3SLC6A12 | |
| SCHEMBL8525768 | 0.76 | SIGMAR1 (0.61) | SIGMAR1DRD2DRD4DRD3SLC6A12 | |
| Hydrochloric Acid SCHEMBL9092182 | 0.75 | SIGMAR1 (0.60) | SIGMAR1DRD2DRD4DRD3SLC6A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539281-B1 | Naphthamides, process for their preparation and their application in the therapeutical field | INST NAT SANTE RECH MED (FR) | 1998-12-30 | — | — | EP | claimed |
| EP-0539281-A1 | New naphthamides, process for their preparation and their application in the therapeutical field | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-04-28 | — | — | EP | claimed |
| EP-0539281-B1 | Naphthamides, process for their preparation and their application in the therapeutical field | INST NAT SANTE RECH MED (FR) | 1998-12-30 | — | — | EP | disclosed |
| US-5498628-A | ANTIPSYCHOTIC, PSYCHOSTIMULATORY, ANTIAUTISTIC, ANTIDEPRESSANT AND HYPOTENSIVE AGENTS, PARKINSON'S DISEASE | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-03-12 | — | — | US | disclosed |
| EP-0539281-A1 | New naphthamides, process for their preparation and their application in the therapeutical field | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-04-28 | — | — | EP | disclosed |